Research reveals a molecule that may help slow aging while on a restricted diet
A multi-institutional team from China and the U.S. has identified a molecule that may play a role in slowing the aging process in some animals consuming a restricted diet. The team has published two papers on their work in ...
New treatment target for neuroendocrine prostate cancer discovered
A team of researchers at Roswell Park Comprehensive Cancer Center, led by Dhyan Chandra, Ph.D., has discovered a new therapeutic target for neuroendocrine prostate cancer, a rare and hard-to-treat form of prostate cancer.
Dec 19, 2024
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Artificially and sugar-sweetened beverages tied to new chronic kidney disease
Higher intakes of artificially sweetened beverages (ASBs) and sugar-sweetened beverages (SSBs) are positively associated with developing chronic kidney disease (CKD), according to a study published online Nov. 25 in Frontiers ...
Dec 19, 2024
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Shiitake-derived functional food shows suppression of liver fibrosis progression
Chronic liver damage can lead to hepatitis, which causes fibrosis of the liver. This buildup of collagen and other fibrous tissue accelerates when hepatic stellate cells become activated during hepatitis, often resulting ...
Dec 19, 2024
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What is metformin's secret sauce? New study shows how 'wonder drug' works in living animals
Millions of people take metformin, a type 2 diabetes medication that lowers blood sugar. The "wonder drug" has also been shown to slow cancer growth, improve COVID outcomes and reduce inflammation. But until now, scientists ...
Dec 18, 2024
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Highly invasive tumor hijacks neurons to grow, but a common heart medication offers hope
Chinese researchers have revealed new insights into the growth of craniopharyngioma and identified a potential therapeutic treatment. Their findings are published online in Science Translational Medicine.
Dec 18, 2024
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FDA: Veozah, first hormone-free hot flash drug, issued black box warning
The U.S. Food and Drug Administration (FDA) has issued its most serious warning—a black-box warning—for Veozah, a medication used to relieve hot flashes in menopausal women, due to rare but potentially severe liver risks.
Dec 18, 2024
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Study on cluster of chemoreceptor cells shows overactive cells linked to type 2 diabetes
Researchers from the University of Missouri are studying potential therapies to target specific cells linked to the development of cardiovascular and metabolic disorders like high blood pressure and type 2 diabetes.
Dec 18, 2024
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Having more chronic conditions may increase older adults' risk of declining kidney function
Older adults with multiple chronic conditions may face a high risk of kidney function decline, according to new research published in the Journal of the American Geriatrics Society.
Dec 18, 2024
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Nonheterosexual women may maintain better sexual functioning during menopause transition, study suggests
A woman's sex drive may diminish with age—partially because of problems with genitourinary symptoms during the menopause transition. Yet, some older women maintain very active sex lives. Why? A new study suggests that one ...
Dec 18, 2024
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Promising therapeutic approach for metabolic liver diseases—researchers target enzyme related to fat metabolism
A MedUni Vienna study has identified a new approach to the drug treatment of metabolic liver diseases. In an experimental study, pharmacological inhibition of an enzyme that plays a central role in fat metabolism promoted ...
Dec 18, 2024
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Flavonoids in polyphenols: Activating gut hormones to improve health
Polyphenols are a diverse group of compounds that contribute to the flavor and health benefits of foods like green tea, berries, and dark chocolate. Among these compounds, flavonoids—responsible for the vibrant colors in ...
Dec 17, 2024
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A simple plasma-based biomarker could predict liver fibrosis in Latino adolescents with obesity
A recent study led by Principal Investigator Michael Goran, Ph.D., and Rachel Schenker, MD, a Fellow in the Children's Hospital Los Angeles Liver Transplant Program, has found a novel combination of plasma-based biomarkers ...
Dec 17, 2024
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Exploring the heterogeneity of metabolic dysfunction-associated steatotic liver disease
About 70% of obese people have metabolic dysfunction-associated steatotic liver disease (MASLD). However, MASLD is also found in lean people. Paradoxically, some effective pharmacological approaches to improve liver health ...
Dec 16, 2024
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An unexpected side effect: Intermittent fasting may slow hair regrowth
Intermittent fasting has proven benefits for metabolic health, but a new study shows that it could slow hair growth—at least in mice. Researchers report December 13 in the journal Cell that mice subjected to intermittent ...
Dec 13, 2024
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Limiting intake of a non-essential amino acid brings surprising benefits in fruit fly study
Feeding female fruit flies a diet low in the amino acid tyrosine improves their ability to endure food shortage, reduces their reproductive output, and causes them to live longer, RIKEN researchers have found. The findings, ...
Dec 12, 2024
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Scientists establish novel link between T cell nutrition and identity
The decision between scrambled eggs or an apple for breakfast probably won't make or break your day. However, for your cells, a decision between similar microscopic nutrients could determine their entire identity. If and ...
Dec 12, 2024
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Ethyl lactate identified as potential therapeutic for alcohol-associated liver disease
A research team led by Prof. Li Yu from the Shanghai Institute of Nutrition and Health (SINH) of the Chinese Academy of Sciences (CAS) and collaborators have uncovered that ethyl lactate, a main nonethanol ingredient found ...
Dec 12, 2024
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Gene expression differences in fat tissue may inform targeted treatment for obesity
New research reveals significant differences in gene expression related to metabolism, inflammation and cardioprotection in the fat tissue of lean and obese mice. These findings could advance the development of targeted therapies ...
Dec 12, 2024
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Research reveals new insights about how 'bad' cholesterol works in the body
National Institute of Health (NIH) scientists have made a significant breakthrough in understanding how "bad" cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were ...
Dec 11, 2024
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Britain indefinitely bans puberty blockers for children with gender dysphoria
The British government on Wednesday indefinitely banned puberty blockers for children with gender dysphoria after independent experts found there was an unacceptable safety risk in prescribing the medication.
Dec 11, 2024
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Researchers unlock new gene therapy targets for diabetic kidney disease
New potential therapeutic targets have been identified for diabetic kidney disease (DKD)—the leading cause of kidney failure in the world—that could see patients treated with new gene and drug therapies preventing the ...
Dec 10, 2024
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Cortisol spikes cause debilitating bone growth in spinal injury patients
Queensland researchers have solved the century-old mystery of why patients who suffer severe spinal cord and brain injuries develop debilitating bone growths around joints such as hips and shoulders.
Dec 10, 2024
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