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Medical research
Study reveals macrophages' misunderstood role in lung fibrosis
Researchers at National Jewish Health and colleagues have completed the first study comparing lung macrophages in multiple models of lung injury. The research indicates that macrophages previously described as "pro-fibrotic" ...
24 minutes ago
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Psychology & Psychiatry
Lifelong singles differ in personality traits and life satisfaction compared to partnered people, study reveals
Although being married or in a long-term relationship is often seen as the norm, more people are staying single for life. But singlehood can bring economic and medical disadvantages, especially as people get older and may ...
25 minutes ago
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Investigation uncovers poor quality of dental coverage under Medicare Advantage
Medicare Advantage—the privatized form of Medicare that offers benefits beyond traditional Medicare, such as dental insurance—is gaining in popularity, but a new analysis reveals that the quality of dental coverage offered ...
18 hours ago
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Novel biomarker catches aging cells in the act
Mayo Clinic researchers have identified interleukin-23 receptor (IL-23R) as a significant biomarker of cellular senescence and aging in both mice and humans. Experiments show that IL-23R levels in the bloodstream increase ...
Reprogramming cells for heart repair: New method transforms ordinary fibroblasts into mature cardiomyocytes
Cardiovascular disease continues to lead as the primary cause of death across the globe, taking millions of lives every year. Damage caused by these diseases is particularly difficult to repair, since the heart has minimal ...
Dec 24, 2024
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Engineered T cells could help patients overcome resistance to CAR T cell therapy
Physician-researchers with City of Hope have developed a way to add features to T cells to help them overcome mechanisms of chimeric antigen receptor (CAR) T cell therapy resistance. Their new system is outlined in a paper ...
Dec 24, 2024
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Engineering a smile: Stem cell–based conduits restore facial nerve function in animal study
A gesture as simple as a smile can often convey what words cannot. This is part of why nonverbal communication is so central to human interaction. It is also why facial nerve disorders and injuries can be devastating.
Dec 24, 2024
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New lung scanning method can show treatment effects in real time
A new method of scanning lungs is able to show the effects of treatment on lung function in real time and enable experts to see the functioning of transplanted lungs.
Dec 24, 2024
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How does being born preterm affect long-term health?
Liggins Institute in Auckland-led research has found that adults who were born preterm showed no statistically significant differences in diabetes, prediabetes, or dyslipidemia and had fewer cardiovascular events compared ...
Newly discovered mechanism reveals NAD's role in aging and disease
UiB researchers are behind a new discovery that tells us how associated neurodegenerative diseases might develop. At the center of this discovery stands a molecule called NAD, or nicotinamide adenine dinucleotide. The results ...
Dec 23, 2024
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Migraine relief: New drug may start working right away
A drug recently approved to prevent migraine may start working right away, according to a study published in the December 23, 2024, online issue of Neurology. The study looked at the drug atogepant, which is a calcitonin ...
Dec 23, 2024
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Unclogging the immune system: Scientists use immunotherapy to remove aging cell buildup
Whenever a sink overflows, the flooding is usually caused by a blockage that has built up in the drains. Similarly, as we age, our bodies are flooded by aging, or senescent cells, which have stopped dividing but, instead ...
Dec 23, 2024
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Digital twin research finds colon cancer cells can be reverted to normal cells
Despite the development of numerous cancer treatment technologies, the common goal of current cancer therapies is to eliminate cancer cells. This approach, however, faces fundamental limitations, including cancer cells developing ...
Dec 23, 2024
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Peptide-based eye drops show promise in treating age-related macular degeneration
Age-related macular degeneration (AMD) is the leading cause of vision loss in individuals over 65, characterized by abnormal changes in the macular, resulting in reduced vision and distorted objects. Dry AMD accounts for ...
Dec 23, 2024
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Pet dogs linked to antimicrobial-resistant Salmonella spread
Antibiotic-resistant Salmonella is a serious public health concern that has increased in recent years as the bacteria have developed ways to survive drugs. According to the U.S. Centers for Disease Control and Prevention, ...
Dec 23, 2024
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Previously unknown protein interactions may lead to better HIV treatments
The human immune deficiency virus (HIV) first entered public consciousness in the early 1980s, after cases of unfamiliar and deadly illnesses began to overwhelm medical centers across North America.
Dec 23, 2024
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Lithium shows promise in treating autism-related symptoms in mouse study
A discovery has highlighted lithium—a drug long used to treat bipolar disorder and depression—as a potential therapy for autism spectrum disorder (ASD). This research, conducted by a team at the Center for Synaptic Brain ...
Dec 23, 2024
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Brain map clarifies neuronal connectivity behind motor function
Signals relayed to motor neurons from the brain enable muscle movement, but these signals typically pass through spinal interneurons before they reach their destination. How the brain and this highly diverse group of "switchboard ...
Dec 23, 2024
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Gene editing tool reduces Alzheimer's plaque precursor in mice
A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers ...
Dec 23, 2024
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Alzheimer's progression tied to stress-induced microglial lipid release
Researchers with the Advanced Science Research Center at the CUNY Graduate Center (CUNY ASRC) have unveiled a critical mechanism that links cellular stress in the brain to the progression of Alzheimer's disease (AD).
Dec 23, 2024
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